James M Downey Selected Research

James M Downey Research Topics

Disease

59	Infarction (Infarctions) 01/2020 - 01/2002
36	Ischemia 11/2021 - 01/2002
13	Myocardial Infarction 10/2018 - 05/2002
7	Reperfusion Injury 11/2021 - 11/2003
6	Coronary Occlusion 10/2013 - 09/2004
5	Thrombosis (Thrombus) 01/2020 - 05/2013
5	Hypothermia 03/2014 - 12/2010
4	Myocardial Ischemia (Ischemic Heart Diseases) 01/2016 - 04/2004
3	Necrosis 01/2016 - 03/2011
3	Acidosis 03/2011 - 04/2007
2	Inflammation (Inflammations) 11/2021 - 04/2010
2	Heart Failure 01/2020 - 10/2018
2	Acute Coronary Syndrome 04/2015 - 03/2014
1	Hemorrhage 01/2020
1	ST Elevation Myocardial Infarction 01/2019
1	No-Reflow Phenomenon 11/2017

Drug/Important Bio-Agent (IBA)

12	Adenosine (Adenocard)FDA LinkGeneric 01/2019 - 01/2002
10	cangrelorIBA 01/2020 - 04/2013
9	Adenosine Triphosphate (ATP)IBA 01/2016 - 08/2002
8	Purinergic P1 Receptors (Adenosine Receptor)IBA 06/2012 - 03/2004
8	triphenyltetrazoliumIBA 09/2008 - 09/2002
6	Phosphotransferases (Kinase)IBA 07/2011 - 01/2005
5	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 01/2019 - 05/2013
5	Purinergic P2Y Receptor AntagonistsIBA 10/2018 - 03/2014
5	WortmanninIBA 10/2013 - 02/2003
5	chelerythrineIBA 10/2013 - 05/2006
5	BradykininIBA 03/2008 - 03/2004
4	Proteins (Proteins, Gene)FDA Link 11/2021 - 03/2004
4	TicagrelorIBA 01/2019 - 10/2013
4	BuffersIBA 01/2019 - 08/2002
4	Opioid Analgesics (Opioids)IBA 01/2016 - 03/2004
4	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 05/2012 - 07/2006
4	BAY 60-6583IBA 05/2011 - 09/2007
4	Cyclic GMP-Dependent Protein Kinases (Protein Kinase G)IBA 07/2009 - 08/2004
4	mitochondrial K(ATP) channelIBA 07/2009 - 05/2002
4	Adenosine-5'-(N-ethylcarboxamide) (NECA)IBA 09/2007 - 03/2004
4	5-hydroxydecanoic acidIBA 04/2007 - 08/2002
4	Acetylcholine (Acetylcholine Chloride)FDA Link 04/2005 - 08/2002
3	cariporideIBA 03/2014 - 10/2002
3	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 05/2012 - 07/2006
3	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 03/2011 - 04/2007
3	SB 216763IBA 12/2010 - 07/2006
3	NG-Nitroarginine Methyl Ester (L-NAME)IBA 12/2010 - 01/2006
3	Oxygen (Dioxygen)IBA 09/2008 - 04/2007
3	Mitochondrial Permeability Transition PoreIBA 09/2008 - 07/2006
3	Free Radical ScavengersIBA 07/2008 - 08/2002
3	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2007 - 08/2002
3	OxadiazolesIBA 07/2006 - 08/2004
3	Ethanol (Ethyl Alcohol)IBA 04/2004 - 05/2002
2	Phosphates (Orthophosphate)IBA 11/2021 - 01/2019
2	Crystalloid SolutionsIBA 01/2019 - 12/2003
2	Purinergic P1 Receptor AntagonistsIBA 01/2019 - 06/2012
2	Clopidogrel (Plavix)FDA Link 01/2019 - 05/2013
2	belnacasanIBA 10/2018 - 11/2017
2	interleukin-1beta-converting enzyme inhibitorIBA 10/2018 - 11/2017
2	Peptides (Polypeptides)IBA 11/2017 - 12/2003
2	Opioid Receptors (Opioid Receptor)IBA 01/2016 - 06/2012
2	LigandsIBA 01/2016 - 07/2008
2	Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA 10/2013 - 01/2005
2	FluorocarbonsIBA 06/2012 - 02/2007
2	Theophylline (Theon)FDA LinkGeneric 06/2012 - 01/2005
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 05/2011 - 03/2006
2	Soluble Guanylyl CyclaseIBA 12/2010 - 07/2006
2	N- (4- cyanophenyl)- 2- (4- (2,3,6,7- tetrahydro- 2,6- dioxo- 1,3- dipropyl- 1H- purin- 8- yl)- phenoxy)acetamideIBA 09/2008 - 05/2006
2	Protein Kinase CIBA 09/2008 - 04/2007
2	Glycine (Aminoacetic Acid)FDA LinkGeneric 07/2008 - 04/2007
2	AutacoidsIBA 03/2008 - 10/2003
2	Leucine-2-Alanine Enkephalin (Enkephalin, Leucine 2 Alanine)IBA 04/2007 - 03/2004
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 05/2006 - 09/2004
2	Guanylate Cyclase (Guanylyl Cyclase)IBA 01/2005 - 08/2004
2	Potassium Channels (Potassium Channel)IBA 12/2003 - 08/2002
2	4- (7- ((2- 3- chloro- 2- thienyl)- 1- methyl- propylamino)- 3H- imidazo(4,5- b)pyridyl- 3- yl)cyclopentane carboxamideIBA 11/2003 - 10/2002
2	Diazoxide (Hyperstat)FDA Link 08/2002 - 05/2002
1	Purinergic P2X7 ReceptorsIBA 11/2021
1	Toll-Like Receptors (Toll-Like Receptor)IBA 11/2021
1	Pyruvic Acid (Pyruvate)IBA 11/2021
1	MicroRNAs (MicroRNA)IBA 11/2021
1	Oxidoreductases (Dehydrogenase)IBA 11/2021
1	Caspase 1 (ICE Protease)IBA 11/2021
1	EnzymesIBA 11/2021
1	Adrenergic Receptors (Adrenergic Receptor)IBA 11/2021
1	InterleukinsIBA 11/2021
1	Toll-Like Receptor AgonistsIBA 11/2021
1	InflammasomesIBA 11/2021
1	Platelet Activating FactorIBA 01/2019
1	Protect-ItIBA 01/2019
1	CytokinesIBA 01/2019
1	ProdrugsIBA 10/2018
1	Pharmaceutical PreparationsIBA 10/2018
1	Coloring Agents (Dyes)IBA 11/2017
1	Cannabinoid Receptor AgonistsIBA 01/2016
1	CannabinoidsIBA 01/2016
1	Cannabinoid Receptors (Cannabinoid Receptor)IBA 01/2016
1	Deoxyribonucleases (DNase)FDA Link 03/2015

Therapy/Procedure

10	Ischemic Postconditioning 11/2017 - 05/2006
6	Therapeutics 11/2017 - 01/2008
3	Stents 01/2020 - 05/2013
2	Microspheres (Microsphere) 11/2017 - 07/2008
2	Liquid Ventilation 06/2012 - 02/2007
1	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 01/2020